Monday, May 27, 2013

PPI Long Term Warnings -- Proton pump inhibitors

I am very thankful that my GERD is not too bad and that I seldom need to take a PPI.  It is controlled well with what I eat and how much I eat.

There are a few things that you need to know, if you are on PPI's for a long time (1 year or longer):

  1. Broken Bones are more common.  Have your physician monitor your Vitamin D and Calcium levels.

  2. Low magnesium.  Don't think it's important?  Low magnesium can cause: muscle spasms, tremors, irregular heartbeats, and seizures.

  3. Low Vitamin B12.   This can cause: Weakness, Anemia, numbness/tingling of hands/feet, memory problems, soreness of the tongue and mouth.

  4. Bacteria Pneumonia.  Since the stomach has less acid to destroy the bacteria's in it, there is a greater chance of bacteria infections.

  5. Effects drug digestion.  The amount of time a drug is broken down in the stomach can be reduced, making it less effective.  If you have gastroparesis too, it is unknown how long a drug can take to process in your stomach -if at all.

  6. Zinc deficiency.  This has so many complications with our body, it is too great to list.  Serious are:  inflammatory bowel disease, increased allergic sensitivity, behavioral and sleep disturbances, mild anemia, hair loss,


pill 2


Here are a few resource links if you want to read more:

  • http://www.fda.gov/Drugs/DrugSafety/ucm245011.htm

  • http://stopacidrefluxpro.com/ppis-side-effects/

  • http://www.pdrhealth.com/proton-pump-inhibitors/side-effects-and-safety-of-proton-pump-inhibitors

  • http://en.wikipedia.org/wiki/Proton-pump_inhibitor

  • http://www.nutritional-supplements-health-guide.com/zinc-deficiency-symptoms.html